YOUR HEART'S MESSAGE

WHEN TO

SUSPECT

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How can you tell if you or someone you love might have transthyretin amyloid cardiomyopathy (ATTR-CM)?

UNDERSTAND THE SIGNS AND SYMPTOMS

Did you know that some seemingly unrelated signs and symptoms could be caused by ATTR-CM? Your body may be sending you a message.

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Fatigue

(excessive tiredness)

“I’m tired all of the time.”

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Tendon Rupture

(eg, biceps, Achilles tendon)

“There is a painful lump in my upper arm.”

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Gastrointestinal Issues

(eg, diarrhoea, constipation, nausea, or feeling full quickly)

“It seems like my stomach is more sensitive lately.”

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Shoulder, Hip, and/or Knee Pain

“It’s been years since I had my hip replaced.”

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Swelling in Lower Legs

(known as peripheral oedema)

“My lower legs and feet look swollen and puffy all the time these days.”

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“I have a past medical history of glaucoma.”

Eye Disorders

(eg, glaucoma)
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“Sometimes I feel like I can't catch my breath.”

Shortness of Breath

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“My doctor says I have an abnormal heartbeat.”

Irregular Heartbeat

(known as cardiac arrhythmia)
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“I’ve had carpal tunnel syndrome in both wrists for years now.”

Bilateral Carpal Tunnel Syndrome

(numbness, tingling, or pain in your fingers)
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“My doctor told me my back pain is caused by something called lumbar spinal stenosis.”

Pain or Numbness in Lower Back/Legs Due to Narrowing of Lower Spine

(known as lumbar spinal stenosis)
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“It feels like my feet are always falling asleep.”

Decreased or Strange Tingling Sensation/Pain in Toes/Feet

(known as peripheral neuropathy)
These examples are for illustrative purposes only. Signs and symptoms may vary from patient to patient.

If your doctor suspects ATTR-CM, they may conduct certain diagnostic tests.

PP-VYN-IRL-0345 |AUG2025